Thermo Fisher Scientific ABCA9 Polyclonal Antibody
Human ABCA9 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ABCA9. Recombinant protein control fragment (Product #RP-101389) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637528 |
Product Specific Information
Immunogen sequence:
FWFQHGRANH VVLENETDSD PTPNDCFEP
Highest antigen sequence identity to the following orthologs:
- Mouse: 62%
- Rat: 62%
Target Information
ABCA9 (ATP-binding cassette, sub-family A (ABC1), member 9) is a 1,624 amino acid protein belonging to the ABC transporter superfamily and the ABCA family.
The ABC1 subfamily is exclusive to multicellular eukaryotes.
ABCA9 is ubiquitously expressed, with high expression in heart, brain, and fetal tissues.
It is a multi-pass membrane protein containing two ABC transporter domains and exists as five alternatively spliced isoforms.
ABCA9 may play a role in monocyte differentiation and lipid homeostasis.
It is up-regulated during monocyte differentiation into macrophages and down-regulated by cholesterol loading of macrophages.
Spanning 85 kb, ABCA9 contains 39 exons, with a non-coding first exon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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