Thermo Fisher Scientific IRF1 Recombinant Rabbit Monoclonal Antibody (BLR039F)
IRF1 단백질을 표적으로 하는 재조합 토끼 단클론 항체. Western blot, IHC, ICC, Flow Cytometry, IP 등 다양한 응용에 적합. HEK293 세포에서 발현된 IgG 형식으로 고순도 정제. 인간 시료 반응성, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 to 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 to 1:500 |
| Flow Cytometry (Flow) | 1 µL / 1×10^6 cells |
| Immunoprecipitation (IP) | 20 µL / 1 mg lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR039F |
| Immunogen | Peptide representing a region between residue 250 and 300 of human interferon regulatory factor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 250 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 7.8–8.6, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Target Information
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family.
IRF1 acts as an activator of interferons alpha and beta transcription and is required for double-stranded RNA induction of these genes in mouse models.
It functions as a transcription activator of genes induced by interferons alpha, beta, and gamma, and plays roles in regulating apoptosis and tumor suppression.
Diseases associated with IRF1 include gastric cancer (somatic) and lung cancer.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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