Thermo Fisher Scientific EphA1 Polyclonal Antibody
Thermo Fisher Scientific의 EphA1 Polyclonal Antibody는 인간 및 마우스 반응성을 가지며 Western blot과 ELISA에 적합합니다. Rabbit IgG 폴리클론 항체로, 세포막 단백질 EphA1을 검출합니다. 액상 형태로 -20°C 보관하며, 연구용으로 사용됩니다.
- 카탈로그번호
- PA5121089
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–230 of human EPHA1 (NP_005223.4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914661 |
Product Specific Information
Positive test controls include: BT-474, HT-29, Mouse liver, Mouse lung, Mouse kidney.
The target is usually found in the following locations: Cell membrane, Single-pass type I membrane protein.
Immunogen sequence:
MERRWPLGLG LVLLLCAPLP PGARAKEVTL MDTSKAQGEL GWLLDPPKDG WSEQQQILNG TPLYMYQDCP MQGRRDTDHW LRSNWIYRGE EASRVHVELQ FTVRDCKSFP GGAGPLGCKE TFNLLYMESD QDVGIQLRRP LFQKVTTVAA DQSFTIRDLV SGSVKLNVER CSLGRLTRRG LYLAFHNPGA CVALVSVRVF YQRCPETLNG LAQFPDTLPG PAGLVEVAGT
Target Information
EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family.
EPH and EPH-related receptors are involved in mediating developmental events, particularly in the nervous system.
Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and two fibronectin type III repeats.
Ephrin receptors are divided into two groups based on extracellular domain sequence similarity and ligand affinity (ephrin-A or ephrin-B).
EphA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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