Thermo Fisher Scientific EphA1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

Positive test controls include: BT-474, HT-29, Mouse liver, Mouse lung, Mouse kidney.
The target is usually found in the following locations: Cell membrane, Single-pass type I membrane protein.

Immunogen sequence:
MERRWPLGLG LVLLLCAPLP PGARAKEVTL MDTSKAQGEL GWLLDPPKDG WSEQQQILNG TPLYMYQDCP MQGRRDTDHW LRSNWIYRGE EASRVHVELQ FTVRDCKSFP GGAGPLGCKE TFNLLYMESD QDVGIQLRRP LFQKVTTVAA DQSFTIRDLV SGSVKLNVER CSLGRLTRRG LYLAFHNPGA CVALVSVRVF YQRCPETLNG LAQFPDTLPG PAGLVEVAGT

Target Information

EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family.
EPH and EPH-related receptors are involved in mediating developmental events, particularly in the nervous system.
Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and two fibronectin type III repeats.
Ephrin receptors are divided into two groups based on extracellular domain sequence similarity and ligand affinity (ephrin-A or ephrin-B).
EphA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.