Thermo Fisher Scientific NCBP2 Polyclonal Antibody
Thermo Fisher Scientific의 NCBP2 Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 rabbit IgG 항체로, WB, ICC/IF, ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 안정적인 PBS/glycerol buffer, 연구용 핵 캡 결합 단백질 분석에 이상적입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–156 of human NCBP2 (NP_031388.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.49 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914659 |
Product Specific Information
- Positive test controls: MCF7, Jurkat, SKOV3, HeLa, NIH/3T3
- Target localization: Cytoplasm, Nucleus
Immunogen sequence:
MSGGLLKALR SDSYVELSQY RDQHFRGDNE EQEKLLKKSC TLYVGNLSFY TTEEQIYELF SKSGDIKKII MGLDKMKKTA CGFCFVEYYS RADAENAMRY INGTRLDDRI IRTDWDAGFK EGRQYGRGRS GGQVRDEYRQ DYDAGRGGYG KLAQNQ
Target Information
The NCBP2 gene encodes a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5′ cap of nascent pre-mRNA in the nucleoplasm. This protein contains an RNP domain typical of RNA-binding proteins and exhibits cap-binding activity. The CBC facilitates pre-mRNA splicing, 3′-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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