Thermo Fisher Scientific Carbonic Anhydrase IX Monoclonal Antibody (GT546)
Human Carbonic Anhydrase IX 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot에 최적화(1:500~1:3,000 희석). 단백질 G 정제, 무보존액 PBS 용액형. 저온 보관(-20°C 장기보관). 저산소 환경에서 CA IX 발현 연구에 적합.
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Thermo Fisher Scientific Carbonic Anhydrase IX Monoclonal Antibody (GT546)
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Publications: N/A
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT546 |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human Carbonic Anhydrase IX |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787126 |
Product Specific Information
- Keep as concentrated solution.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues.
CA IX is one of the most inducible genes under hypoxia via HIF-1 alpha due to its stability and membrane localization.
Carbonic anhydrases regulate pH in normal tissues by controlling hydrogen ion (H⁺) flux.
Blockade of CA IX increases cell death under hypoxia, making CA IX a reliable histochemical marker of hypoxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-31495_Carbonic_Anhydrase_IX_Q16790-1_House_mouse.svg, MA5-31495_Carbonic_Anhydrase_IX_Q16790-1_House_mouse_PDP.jpeg)
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