Thermo Fisher Scientific WBP1L Monoclonal Antibody (OPAL1-01)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

-

Flow Cytometry (Flow)

1-4 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

OPAL1-01

Immunogen

Recombinant fragment of human OPAL1 (amino acids 152-342) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:WBP1L,uniProtId:Q9NX94-1,ncbiNodeId:9606,antigenRange:152-342,antigenLength:342,antigenImageFileName:MA5-28627_WBP1L_Q9NX94-1_House_mouse.svg,antigenImageFileNamePDP:MA5-28627_WBP1L_Q9NX94-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

View additional formats

• PE
• Request custom conjugation

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 8

Contains

15mM sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_2745586

Product Specific Information

This antibody recognizes an intracellular epitope of OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megakaryocytes and platelets.

Western Blot: non-reducing conditions recommended.

Target Information

WBP1L (OPAL1, outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megakaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.