Thermo Fisher Scientific NeuN Polyclonal Antibody
NeuN 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·마우스·랫트에 반응합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 액상 형태로 PBS에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5143567
- 판매단위
- pk
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Thermo Fisher Scientific NeuN Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:5,000–1:10,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:5,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | N-terminal 100 amino acids of human FOX3 expressed and purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2942796 |
Target Information
Fox-3, also known as NeuN, HRNBP3, RBFOX3 (RNA binding protein, fox-1) or Fox-1 homolog C, is a 350-amino-acid protein containing one RRM (RNA recognition motif) domain. It is localized to both the nucleus and cytoplasm and is suggested to regulate alternative splicing events.
Fox-3 is encoded by a gene located on human chromosome 17, which represents over 2.5% of the human genome and encodes more than 1,200 genes. Two key tumor suppressor genes, p53 and BRCA1, are associated with chromosome 17.
- p53 maintains genomic integrity through DNA repair and cell fate regulation.
- BRCA1 is involved in DNA repair and is linked to early-onset breast cancer and predisposition to cancers of the ovary, colon, prostate, and fallopian tubes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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