Thermo Fisher Scientific CD19 Monoclonal Antibody (SJ25C1), PE, eBioscience
인간 CD19 항원을 인식하는 SJ25C1 클론의 단클론 항체로, PE 형광체가 결합된 형태입니다. Flow cytometry에 최적화되어 있으며, B세포 발현 분석에 사용됩니다. 4°C 어둠에서 보관하며, 동결 금지. 연구용 전용 시약입니다.
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Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 5 µL (0.06 µg)/test
- Publications: View 17 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SJ25C1 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10734045 |
Available Conjugate Formats
- Alexa Fluor 488
- Alexa Fluor 532
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 395, 496, 615, 737, 805
- Brilliant Violet 605, 650
- eFluor 450, 506
- NovaFluor Blue 610-70S, 660-120S, 690
- NovaFluor Red 685, 725, 755
- NovaFluor Yellow 590, 610, 690, 755
- PE-Cyanine5.5, PE-Cyanine7, PE-eFluor 610
- PerCP-Cyanine5.5, PerCP-eFluor 710
- Super Bright 436, 600, 645, 702, 780
- Request custom conjugation
Product Specific Information
Description:
The SJ25C1 monoclonal antibody reacts with human CD19, a 95 kDa transmembrane glycoprotein expressed on B cells throughout development except for terminally differentiated plasma cells. Follicular dendritic cells also express CD19. This molecule forms a multimolecular complex with CD21, CD81, Leu13, and MHC class II, associated with the B cell receptor (BCR). Signaling through CD19 induces tyrosine phosphorylation, calcium flux, and B cell proliferation. The SJ25C1 and HIB19 antibodies recognize overlapping epitopes.
Applications Reported:
This antibody is reported for use in flow cytometric analysis.
Applications Tested:
Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. Recommended use at 5 µL (0.06 µg) per test in a final volume of 100 µL. Suitable for 10⁵–10⁸ cells/test.
Excitation / Emission:
488–561 nm / 578 nm (Blue, Green, Yellow-Green lasers)
Filtration:
0.2 µm post-manufacturing filtered.
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on nearly all peripheral B cells and certain myeloid leukemia cells. CD19 acts as a signal-amplifying coreceptor for the B cell receptor (BCR) and regulates normal and malignant B cell proliferation. Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression causes B cell hyperactivity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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