Thermo Fisher Scientific Thyroglobulin Recombinant Rabbit Monoclonal Antibody (1G2T10)
Thyroglobulin을 표적으로 하는 재조합 토끼 단클론 항체로, IHC(P) 및 ICC/IF에 적합합니다. HEK293 세포에서 발현되었으며, 비결합(Unconjugated) 상태로 제공됩니다. 인간 갑상선 관련 연구 및 자가면역 질환 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 – 1:200 |
| Immunocytochemistry (ICC/IF) | 1:50 – 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1G2T10 |
| Immunogen | A synthesized peptide derived from human Thyroglobulin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.85 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911949 |
Target Information
The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3.
Thyroid disorders are largely of autoimmune origin, and anti-thyroglobulin autoantibodies were the first to be discovered.
Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves disease), with the highest levels observed in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow-up of cancer patients.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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