Thermo Fisher Scientific HIP1R/HIP12 Polyclonal Antibody
HIP1R/HIP12 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 시료에 반응합니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1018 to 1068 of human Huntingtin-interacting protein 1-related protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Huntingtin disease is a neurodegenerative disorder caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of this disease.
HIP-1 also plays a role in clathrin coat recruitment to lipid membranes and may contribute to tumorigenesis by supporting the survival of precancerous and cancerous cells.
Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, it can serve as a putative prognostic factor for these cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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