
Thermo Fisher Scientific HIP1R/HIP12 Polyclonal Antibody
HIP1R/HIP12 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체로, 인간 시료에 반응하며 4°C에서 보관.
- 카탈로그번호
- A304805A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 300–350 of human Huntingtin-interacting protein 1-related protein (HIP1R) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Huntingtin disease, a neurodegenerative disorder, is caused by expansion of a polymorphic glutamine tract in huntingtin. Huntingtin Interacting Protein 1 (HIP-1) is a proapoptotic, cargo-specific adaptor protein potentially involved in the pathogenesis of Huntingtin disease. HIP-1 also plays a role in clathrin coat recruitment to lipid membranes and may contribute to tumorigenesis by supporting survival of precancerous and cancerous cells. HIP-1 expression correlates significantly with prostate and colon cancer metastasis, making it a putative prognostic factor for these cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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