Thermo Fisher Scientific ALDH18A1/P5CS Polyclonal Antibody
Rabbit polyclonal antibody against human ALDH18A1/P5CS for WB and IP applications. Recognizes region 575–625 of ALDH18A1. Unconjugated, liquid form at 1 mg/mL. Stored at 4°C, shipped on wet ice. Predicted cross-reactivity with Orangutan.
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Applications
Western Blot (WB)
- Tested Dilution: 1:10,000–1:25,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 575 to 625 of human Aldehyde Dehydrogenase 18 Family, Member A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
This gene belongs to the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities.
It catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a crucial step in the de novo biosynthesis of proline, ornithine, and arginine.
Mutations in this gene can lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia, and hypoprolinemia, and may be associated with neurodegeneration, cataracts, and connective tissue diseases.
Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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