Thermo Fisher Scientific CTLA-4 (CD152) Chimeric Recombinant Rabbit Monoclonal Antibody (9D9)
CTLA-4 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, 마우스 시료에 반응합니다. 면역세포 활성 억제 연구에 적합하며, ICC/IF 및 억제 분석에 사용 가능합니다. Protein A로 정제된 액상 항체로, 1 mg/mL 농도이며 4°C 또는 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Inhibition Assays (IA) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9D9 |
| Immunogen | The antibody was raised against CTLA-4. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074572 |
Product Specific Information
Specificity: The antibody is specific for CTLA-4.
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed mainly on CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity. Unlike CD28, which enhances cell function, CTLA4 inhibits T cell activation and prevents its function. Intracellular CTLA4 is also found in regulatory T cells and may be essential for their function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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