Thermo Fisher Scientific Phospho-14-3-3 theta (Ser232) Polyclonal Antibody
Rabbit polyclonal antibody recognizing phospho-14-3-3 theta (Ser232). Validated for WB, IHC(P), and ICC/IF. Supplied as liquid, 1 mg/mL, unconjugated. Suitable for research use in signaling pathway studies.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human 14-3-3 theta/tau around the phosphorylation site of Ser232 (S-D-SP-A-G) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554997 |
Target Information
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5′ UTR a 6 bp tandem repeat sequence which is polymorphic; however, there is no correlation between the repeat number and the disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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