Thermo Fisher Scientific MTM1 Polyclonal Antibody
제브라피시에서 반응하는 Rabbit Polyclonal 항체로, MTM1 단백질 검출에 사용됩니다. Western blot에 최적화되어 있으며, 단백질 A 및 항원 친화 크로마토그래피로 정제되었습니다. PBS 완충액에 보관되며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5116357
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- pk
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1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MTM1 Polyclonal Antibody
Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 451–485 amino acids from the region of DANRE mtm1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900991 |
Target Information
Human MTM1 is a 603 amino-acid protein mutated in myotubular myopathy. The related protein hMTMR2 is mutated in a recessive form of Charcot-Marie-Tooth neuropathy. Myotubularin functions as a lipid phosphatase acting on phosphatidylinositol 3-monophosphate, regulating the PI 3-kinase pathway and membrane trafficking. Wild-type myotubularin directly dephosphorylates PI 3-P and PI 4-P in vitro, reducing PI 3-P levels by down-regulating PI 3-K activity and facilitating PI 3-P degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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