Thermo Fisher Scientific Phospho-Protein vestigial (Ser215) Polyclonal Antibody
Drosophila melanogaster Vestigial 단백질의 Ser215 인산화 부위를 인식하는 rabbit polyclonal antibody. WB, ELISA, IP에 사용 가능하며, 고순도 affinity chromatography로 정제됨. 액상 형태로 -20°C 보관. 연구용 전용 제품.
- 카탈로그번호
- PVSTGL-140AP
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly (D. melanogaster) |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequences on D. melanogaster Vestigial protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This protein is involved in determining which thoracic imaginal disk cells form wings and halteres, possibly through interaction with other nuclear regulatory proteins. In combination with scalloped (sd), it functions as a transcriptional activation complex regulating gene expression in the wing. Binding to sd modifies DNA target selectivity. It is required and sufficient for cell proliferation at the dorsal/ventral (D/V) boundary of the wing imaginal disk and also contributes to proliferation via activation of E2f. Interaction with Dhfr may regulate genes involved in DNA replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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