Thermo Fisher Scientific SLC22A18 Polyclonal Antibody
Human SLC22A18 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 buffer에 40% glycerol 포함. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA566954
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human SLC22A18. Recombinant protein control fragment (Product #RP-107599) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2664353 |
Product Specific Information
- Immunogen sequence: TQGLVIGQLSS HFSEEVLLR
- Antigen sequence identity: Mouse 75%, Rat 70%
Target Information
ORCTL2 (organic cation transporter-like protein 2), also known as HET, ITM, BWR1A, IMPT1, TSSC5, BWSCR1A, SLC22A1L, p45-BWR1A or SLC22A18, is a 424 amino acid multi-pass membrane protein localized at the apical membrane surface of renal proximal tubules.
It is highly expressed in kidney, liver, colon, and fetal renal proximal tubules, with lower expression in heart, brain, and lung.
Belonging to the major facilitator superfamily, ORCTL2 may act as a transporter of organic cations via a proton efflux antiport mechanism and may participate in the transport of chloroquine and quinidine-related compounds in kidney.
Defects in ORCTL2 are associated with breast and lung cancer and rhabdomyosarcoma type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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