Thermo Fisher Scientific EHD1 Polyclonal Antibody
EHD1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human EHD1. Recombinant protein control fragment (Product #RP-105436) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664757 |
Product Specific Information
Immunogen sequence:
MEQPGTAASPV SGSMFSWVSK DARRKKEPEL FQTVAEGLRQ LYAQKLLP
Highest antigen sequence identity to the following orthologs: mouse 71%, rat 71%.
Target Information
EHD1 acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. It also plays a role in myoblast fusion and is recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulating neurite outgrowth.
EHD1 belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The EH domain, first noted in EPS15, is an important motif in proteins involved in protein-protein interactions and intracellular sorting.
EHD1 is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for the EHD1 gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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