Thermo Fisher Scientific Phospho-GATA3 (Ser308) Recombinant Rabbit Monoclonal Antibody (ARC1560)
Phospho-GATA3 (Ser308)을 인식하는 재조합 토끼 단클론 항체로 Western blot 및 ELISA에 적합. HEK293 세포에서 발현되었으며, PBS/glycerol buffer에 보관. T세포 수용체 유전자 조절 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1560 |
| Immunogen | A phospho-specific peptide corresponding to residues surrounding S308 of human GATA3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849761 |
Target Information
The genes for all four subunits of the T-cell antigen receptor (alpha, beta, gamma, and delta) are regulated by distinct enhancers and their binding proteins. GATA3, identified as a common TCR enhancer-binding protein, binds to enhancer elements of all four TCR genes. It contains a zinc finger domain and is abundantly expressed in T-lymphocytes, contributing to T-cell receptor gene activation. The human GATA3 gene consists of six exons over 17 kb, with zinc finger domains encoded by conserved exons similar to GATA1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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