Thermo Fisher Scientific RRAS2 Polyclonal Antibody
RRAS2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 실험에 적합하며, 인간 및 마우스에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공.
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Thermo Fisher Scientific RRAS2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000–1:10,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 1–204 of TC21 (Uniprot ID# P62070) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.69 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, keep at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152467 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain.
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (96%), Xenopus laevis (96%), Chicken (98%), Rhesus Monkey (100%), Bovine (100%).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RRAS2 is involved in activating mutations and the overexpression of classical Ras subfamily members (K-RAS, N-RAS, and H-RAS), which are key events in the development of human cancers.
The RRAS subfamily (RRAS1, RRAS2/TC21, RRAS3/M-Ras) shares 55–60% amino acid identity with classical Ras proteins.
RRAS2 is a small GTP-binding protein of the Ras superfamily that may transduce growth inhibitory signals through shared effectors with Ras proteins.
It has high oncogenic potential, and overexpression/mutations have been reported in several tumor tissues and cell lines.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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