Thermo Fisher Scientific Gemin4 Polyclonal Antibody
Rabbit polyclonal antibody specific for human Gemin4, validated for WB, IHC, and IP. Recognizes residues 1010–1058 of Gemin4 protein. Supplied as liquid, unconjugated form at 0.20 mg/mL. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1010 and the C-terminus (residue 1058) of human Gemin4 (nuclear organelle) Associated Protein 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections
Target Information
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and discrete nuclear bodies called Gemini bodies.
This complex functions in spliceosomal snRNP assembly in the cytoplasm and regenerates spliceosomes required for pre-mRNA splicing in the nucleus.
The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins.
Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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