Thermo Fisher Scientific RBMXL2 Recombinant Rabbit Monoclonal Antibody (2Z6C10)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2Z6C10

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 175-350 of human RBMXL2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RBMXL2,uniProtId:O75526-1,ncbiNodeId:9606,antigenRange:175-350,antigenLength:392,antigenImageFileName:MA5-55546_RBMXL2_O75526-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55546_RBMXL2_O75526-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: GGMRGRALAV RGRDGYSGPP RREPLPPRRD PYLGPRDEGY SSRDGYSSRD YREPRGFAPS PGEYTHRDYG HSSVRDDCPL RGYSDRDGYG GRDRDYGDHL SRGSHREPFE SYGELRGAAP GRGTPPSYGG GGRYEEYRGY SPDAYSGGRD SYSSSYGRSD RYSRGRHRVG RPDRGL

Target Information

The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.