Thermo Fisher Scientific RBMXL2 Recombinant Rabbit Monoclonal Antibody (2Z6C10)
RBMXL2 단백질을 인식하는 토끼 유래 재조합 단클론 항체. 인간 시료에 반응하며 ICC/IF 및 ELISA에 적합. HEK293 세포에서 발현, Protein A로 정제. 0.2 mg/mL 액상 형태로 제공되며, -20°C에서 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2Z6C10 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 175–350 of human RBMXL2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
GGMRGRALAV RGRDGYSGPP RREPLPPRRD PYLGPRDEGY SSRDGYSSRD YREPRGFAPS PGEYTHRDYG HSSVRDDCPL RGYSDRDGYG GRDRDYGDHL SRGSHREPFE SYGELRGAAP GRGTPPSYGG GGRYEEYRGY SPDAYSGGRD SYSSSYGRSD RYSRGRHRVG RPDRGL
Target Information
The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). They are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing and mRNA metabolism and transport. While most hnRNPs are nuclear, some shuttle between the nucleus and cytoplasm. RBMXL2 contains two RRM domains that bind RNAs and shares similarity with HNRPG and RBMY proteins. It may replace HNRPG function during meiotic prophase or act as a germ cell-specific splicing regulator. RBMXL2 primarily localizes to the nuclei of meiotic spermatocytes and is a candidate gene for autosomal male infertility. This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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