Thermo Fisher Scientific BID Polyclonal Antibody
마우스 BID 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며 1:1,000~1:10,000 희석 비율로 사용. 항원 친화 크로마토그래피로 정제된 액상 항체로 4°C 보관. 세포 사멸 연구용으로 적합.
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Applications
- Western Blot (WB): 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1 and 50 of mouse BH3 interacting domain death agonist (BID) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. It belongs to the BCL-2 family of cell death regulators and mediates mitochondrial damage induced by caspase-8 (CASP8). CASP8 cleaves BID, and the COOH-terminal part translocates to mitochondria to trigger cytochrome c release. In response to TNF alpha or Fas ligand, BID is cleaved and activated, and the C-terminal 15 kDa fragment (p15) moves to mitochondria, initiating apoptosis. BID acts as a direct molecular link between caspase-8 activation and mitochondrial death machinery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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