Thermo Fisher Scientific TGFB2 Polyclonal Antibody
TGFB2 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 및 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 및 글리세롤 완충액 형태로 제공되며, -20°C에서 보관합니다.
- 카탈로그번호
- TA890046
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human TGFB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Transforming Growth Factor (TGF) betas mediate many cell-to-cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals: TGF beta 1, TGF beta 2, and TGF beta 3. Each is synthesized as a precursor protein that is cleaved to yield a 112 amino acid polypeptide associated with its latent portion.
TGF beta polypeptides are multifunctional, influencing cell proliferation, differentiation, and other cellular functions. Both transformed and non-neoplastic tissues release TGF betas, and most mammalian cells possess specific TGF receptors.
TGF beta exhibits multimodal activity, capable of stimulating or inhibiting cellular proliferation. Generally, mesenchymal cells are stimulated, while epithelial or neuroectodermal cells are inhibited. TGF beta 1, beta 2, and beta 1.2 share similar biological activity but may differ in receptor binding.
TGF beta 2 is produced by many cell types, found in highest concentrations in porcine platelets and mammalian bone. Latent TGF beta 2 is the dominant isoform in body fluids such as amniotic fluid, breast milk, and ocular humors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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