Thermo Fisher Scientific P2X2 Polyclonal Antibody
P2X2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, Flow cytometry에 적합하며 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관 가능.
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Thermo Fisher Scientific P2X2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Flow Cytometry (Flow) | 1:50–1:100 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within C-terminal human P2X2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913256 |
Product Specific Information
- Positive Control: Mouse brain tissue lysates, rat brain tissue, human esophagus tissue, MCF-7
- Subcellular Location: Cell membrane
Target Information
P2rx2 belongs to the ligand-gated ion channel family activated by extracellular ATP. Each receptor is composed of a trimer of subunits (P2X1–7) sharing two transmembrane domains. P2rx2 mediates synaptic transmission between neurons and smooth muscle, playing roles in sensory neuron responses, neuromuscular junction formation, hearing, taste perception, and peristalsis.
In the inner ear, P2rx2 is involved in sound transduction, auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K⁺ recycling. Mutations in P2RX2 are associated with autosomal dominant deafness (DFNA41).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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