Thermo Fisher Scientific CD2 Monoclonal Antibody (RPA-2.10), APC, eBioscience
인간 및 비인간 영장류 CD2 단백질을 인식하는 단클론 항체로, APC 형광 표지되어 Flow Cytometry에 최적화됨. T 세포 및 NK 세포 분석용으로 사용 가능하며, 633–647 nm 레이저에서 여기, 660 nm에서 방출. 4°C 어두운 곳 보관, 동결 금지.
- 카탈로그번호
- 17-0029-42
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Frozen)
- Tested Dilution: Not specified
- Publications: View 1 publication
Flow Cytometry
- Tested Dilution: 5 µL (0.125 µg)/test
- Publications: View 8 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Baboon, Chimpanzee, Cynomolgus monkey, Human, Non-human primate, Pig, Rhesus monkey |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RPA-2.10 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10805740 |
Available Formats
- Unconjugated
- Alexa Fluor 700
- APC-eFluor 780
- Biotin
- eFluor 450
- FITC
- Functional Grade
- NovaFluor Blue 510 / 585 / 610-70S / 660-120S / 690
- NovaFluor Yellow 570
- PE
- PE-Cyanine5 / PE-Cyanine7
- PerCP-eFluor 710
- Super Bright 436 / 600 / 645 / 702 / 780
- Request custom conjugation
Product Specific Information
The RPA-2.10 monoclonal antibody reacts with human CD2, a 50 kDa cell surface receptor expressed by most thymocytes, all mature T cells, and a subset of NK cells. CD2 binds CD58 and plays a key role in T-cell adhesion and activation. The RPA-2.10 clone can block mixed lymphocyte reactions and cross-reacts with non-human primates and pigs.
Applications Reported: Flow cytometric analysis
Applications Tested: Pre-titrated and tested by flow cytometry using normal human peripheral blood cells. Recommended use: 5 µL (0.125 µg) per 100 µL test volume.
Excitation: 633–647 nm
Emission: 660 nm
Laser: Red Laser
Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD2 (LFA-2) is a monomeric surface antigen (45–58 kDa) expressed on human T lymphocytes and NK cells, but not on B cells. It mediates adhesion via CD58 interaction, stabilizing T cell–APC contact. CD2 expression increases upon T cell activation, enhancing adhesion and signaling. CD2 deficiency is linked to immune dysfunction and certain carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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