Thermo Fisher Scientific SARS-CoV-2 ORF3a Polyclonal Antibody
SARS-CoV-2 ORF3a 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 ELISA에 적합하며, 고순도 친화 크로마토그래피 정제 제품. 액상 형태로 안정적인 PBS/glycerol buffer 제공. 연구용 전용 시약.
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- PA5116946
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Thermo Fisher Scientific SARS-CoV-2 ORF3a Polyclonal Antibody
Applications 및 Tested Dilution
- Western Blot (WB): 1:2,000–1:6,000
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100–200 of coronavirus ORF3A (YP_0097243911) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901576 |
Product Specific Information
- Positive Samples: 293T
- Immunogen Sequence: GDGTTSPISE HDYQI
Target Information
ORF3A forms homotetrameric potassium-sensitive ion channels (viroporin) and may modulate virus release. It up-regulates expression of fibrinogen subunits FGA, FGB, and FGG in host lung epithelial cells, induces apoptosis in cell culture, and downregulates the type 1 interferon receptor by promoting serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif, increasing IFNAR1 ubiquitination.
주의사항
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
자세한 정보: www.P65Warnings.ca.gov
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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