Thermo Fisher Scientific BRG1 Polyclonal Antibody
BRG1 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA, IP 등 다양한 응용 가능. 인간, 생쥐, 랫트 반응성. 핵 내 BRG1 단백질 검출에 적합하며 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 680–770 of human BRG1/SMARCA4 (NP_003063.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914361 |
Product Specific Information
- Positive test controls: 293T cells
- Subcellular localization: Nucleus
- Immunogen sequence:
PTLPVEEKKK IPDPDSDDVS EVDARHIIEN AKQDVDDEYG VSQALARGLQ SYYAVAHAVT ERVDKQSALM VNGVLKQYQI KGLEWLVSLY N
Target Information
Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that regulate transcription, DNA repair, and replication. Brg1-containing complexes are crucial for transcriptional regulation of genes related to interferon response, immune cell differentiation, neurogenesis, and cell cycle. It is essential for mouse embryogenesis and plays roles in cell growth arrest, senescence, and tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-120789_BRG1_P51532-1_Rabbit.svg, PA5-120789_BRG1_P51532-1_Rabbit_PDP.jpeg)
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