Thermo Fisher Scientific TLR12 Monoclonal Antibody (15F1215)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Mouse / IgM

Class

Monoclonal

Type

Antibody

Clone

15F1215

Immunogen

Amino acids 791-821 of mouse TLR12 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TLR12,uniProtId:Q6QNU9-1,ncbiNodeId:10090,antigenRange:791-821,antigenLength:906,antigenImageFileName:MA1-41484_TLR12_Q6QNU9-1_House_mouse.svg,antigenImageFileNamePDP:MA1-41484_TLR12_Q6QNU9-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites/PBS with 0.2% gelatin

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_1087884

Product Specific Information

Based on sequence homology, this antibody may also detect mouse TLR11.

Target Information

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR12 has been cloned that displays a distinct pattern of expression in macrophages and liver, kidney, and bladder epithelial cells. TLR12 does not respond to known TLR ligands.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.