Thermo Fisher Scientific MRP1 Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
1:200
Immunohistochemistry (Frozen) (IHC (F))
1:100-1:500
Immunocytochemistry (ICC/IF)
1:50-1:200
Flow Cytometry (Flow)
1:10
ELISA (ELISA)
1:500-1:1,000
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from mouse MRP1, amino acids 501-600. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
MRP1,
uniProtId:
O35379-1,
ncbiNodeId:
10090,
antigenRange:
501-600,
antigenLength:
1528,
antigenImageFileName:
BS-0657R_MRP1_O35379-1_Rabbit.svg,
antigenImageFileNamePDP:
BS-0657R_MRP1_O35379-1_Rabbit_PDP.jpeg,
sortOrder:
2}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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