Thermo Fisher Scientific Decorin Recombinant Rabbit Monoclonal Antibody (DCN/8715R)
Recombinant rabbit monoclonal antibody targeting human Decorin. Suitable for IHC (paraffin and PFA fixed) applications. High purity via Protein A/G purification. Supplied as liquid, unconjugated form at 1 mg/mL concentration. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | DCN/8715R |
| Immunogen | Recombinant human Decorin protein fragment (around aa212–336) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Decorin is a member of the small leucine-rich proteoglycan (SLRP) family, along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-β. Decorin is believed to play a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154–Leu155 of the decorin core protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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