Thermo Fisher Scientific DOPA Decarboxylase Polyclonal Antibody
Rabbit polyclonal antibody against human DOPA Decarboxylase (DDC). Validated for WB and ICC/IF. Detects ~55 kDa protein. Suitable for dopaminergic, noradrenergic, and serotonergic neuron studies. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Guinea pig, Human, Sheep, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal region of human DDC conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01 M HEPES, pH 7.5, with 0.15 M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2088961 |
Product Specific Information
This antibody is specific for the ~55 kDa DDC protein in Western blots of rat adrenal medulla.
Target Information
DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin. It is also involved in the biosynthesis of trace amines.
DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic, and serotonergic neurons in a variety of research applications, including studies on depression, schizophrenia, Parkinson’s disease, and drug abuse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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