Thermo Fisher Scientific RUNX3 Monoclonal Antibody (OTI2G1), TrueMAB
RUNX3 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 동결건조 형태로 제공됩니다. 종양 억제 유전자 연구 및 전사인자 분석에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G1 |
| Immunogen | Full length human recombinant protein of human RUNX3 produced in E.coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The RUNX3 gene encodes a member of the runt domain-containing family of transcription factors.
A heterodimer of this protein and a beta subunit binds to the core DNA sequence 5'-PYGPYGGT-3' found in many enhancers and promoters, acting as a transcription activator or suppressor.
It interacts with other transcription factors and functions as a tumor suppressor. The RUNX3 gene is often deleted or silenced in various cancers.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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