Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1/S2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0893)
SARS-CoV-2 Spike 단백질을 인식하는 알파카 유래 재조합 단일클론 항체로 ELISA에 적합합니다. CHO 세포에서 발현되었으며, 1 mg/mL 농도로 PBS에 보존됩니다. 금속 킬레이트 크로마토그래피로 정제되었으며, 비결합형 상태로 제공됩니다.
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Applications
- ELISA (ELISA): Assay-dependent
- Compatible with Direct ELISA
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA0893 |
| Immunogen | Recombinant SARS-CoV-2 S protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The Spike (S) protein is essential for viral attachment, fusion, and entry, and serves as a key target for antibody development, entry inhibitors, and vaccines.
The receptor-binding domain (RBD) of the Spike protein binds strongly to human and bat ACE2 receptors, showing higher affinity than SARS-CoV RBD.
- S1 subunit (aa 14–685): Contains RBD that specifically binds ACE2 receptors.
- S2 subunit (aa 686–1273): Responsible for membrane fusion.
- S-ECD: Extracellular domain of the Spike protein.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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