Thermo Fisher Scientific TIMP2 Monoclonal Antibody (1C3)
TIMP2 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 1C3). Western blot 및 ELISA에 적합하며, 인간 시료 반응성. 액상 형태, 보존제 무첨가, -20°C 보관. 연구용으로만 사용.
- 카탈로그번호
- H00007077-M03C
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C3 |
| Immunogen | TIMP2 (AAH52605, 27–220 a.a.) full-length recombinant protein with GST tag. MW of GST tag alone: 26 kDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Tissue culture supernatant |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
CSCSPVHPQQ AFCNADVVIR AKAVSEKEVD SGNDIYGNPI KRIQYEIKQI KMFKGPEKDI EFIYTAPSSA VCGVSLDVGG KKEYLIAGKA EGDGKMHITL CDFIVPWDTL STTQKKSLNH RYQMGCECKI TRCPMIPCYI SSPDECLWMD WVTEKNINGH QAKFFACIKR SDGSCAWYRG AAPPKQEFLD IEDP
Target Information
TIMP-1 and TIMP-2 are inhibitory enzymes of the matrix metalloproteinase family, important for maintaining connective tissue integrity.
TIMP-2 binds both latent (pro) and active forms of 72 kDa Type IV collagenase (MMP-2 or gelatinase A), and also the active form of 92 kDa Type IV collagenase (MMP-9 or gelatinase B).
It inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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