Thermo Fisher Scientific ME3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ME3. Recombinant protein control fragment (Product #RP-97397). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ME3,uniProtId:Q16798-1,ncbiNodeId:9606,antigenRange:543-604,antigenLength:604,antigenImageFileName:PA5-58408_ME3_Q16798-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58408_ME3_Q16798-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643836

Product Specific Information

Immunogen sequence: DVSLRIAIKV LDYAYKHNLA SYYPEPKDKE AFVRSLVYTP DYDSFTLDSY TWPKEAMNVQ TV

Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 76%.

Target Information

ME3 proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis, metastasis, and atherosclerosis. Most MMP`s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.