Thermo Fisher Scientific NSDHL Polyclonal Antibody
Human NSDHL 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 콜레스테롤 생합성 연구 및 CHILD 증후군 관련 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Category | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NSDHL. Recombinant protein control fragment (Product #RP-91900). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644807 |
Product Specific Information
Immunogen sequence:
MEPAVSEPMR DQVARTHLTE DTPKVNADIE KVNQNQAKRC TVIGGSGFLG QHMVEQLLAR GYAVNVFDIQ QGFDNPQVRF FLGDLCSRQD LYPALKGVNT VFHCASPPPS SNNKELFYRV NYIGT
Antigen sequence identity:
- Mouse: 72%
- Rat: 68%
Target Information
The NSDHL protein is localized in the endoplasmic reticulum and participates in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, an X-linked dominant disorder of lipid metabolism that is typically lethal in males. Alternatively spliced transcript variants with differing 5′ UTRs have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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