Thermo Fisher Scientific PDE1B Monoclonal Antibody (4F9)
PDE1B 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체(4F9). 인간 시료 반응성, Western blot 및 ELISA에 최적. 비결합형 액상 형태로 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F9 |
| Immunogen | PDE1B (AAH32226, 437–536 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
TDVAEKSVQP LADEDSKSKN QPSFQWRQPS LDVEVGDPNP DVVSFRSTWV KRIQENKQKW KERAASGITN QMSIDELSPC EEEAPPSPAE DEHNQNGNLD
Target Information
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, specifically the PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent enzymes stimulated by calcium-calmodulin complexes. PDE1B exhibits dual specificity for cAMP and cGMP, with a preference for cGMP as a substrate. These cyclic nucleotides regulate numerous physiological processes. Multiple alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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