Thermo Fisher Scientific NR4A3 Monoclonal Antibody (OTI4D1), TrueMAB
인간 NR4A3 단백질을 인식하는 마우스 단일클론 항체로, Western blot에 최적화되어 있습니다. 동결건조 형태로 제공되며, PBS 버퍼에 trehalose가 포함되어 안정적입니다. 연구용으로만 사용되며, 재구성 및 결합 실험에 적합합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 332–626 of human NR4A3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
NOR-1 (NR4A3) is a nerve growth factor-like receptor implicated in neuronal development, T-cell apoptosis, and cancer progression. It binds to NBRE (NGFI-B response element) and regulates the POMC gene. NOR-1 expression is transiently induced by various stimuli, and its downregulation correlates with addiction-prone behavior in Lewis rats.
Three human isoforms have been documented: NOR-1, NOR-1β, and NOR-1 3′ variant.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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