Thermo Fisher Scientific CTNNA3 Recombinant Rabbit Monoclonal Antibody (23GB5125)
Thermo Fisher Scientific의 CTNNA3 Recombinant Rabbit Monoclonal Antibody (23GB5125)은 인간, 마우스, 랫트 반응성을 가지며 WB 및 Flow Cytometry에 사용 가능합니다. HEK293F 시스템에서 발현된 고순도 항체로, 액상 형태이며 -20°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5125 |
| Immunogen | A synthesized peptide derived from human CTNNA3 (700–895AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Catenins are proteins that connect cadherin/beta-catenin cell adhesion complexes to the actin cytoskeleton. Although originally discovered in testis, alphaT-catenin is expressed in other tissues, with the highest levels observed in the heart. Immunohistochemical analysis shows human alphaT-catenin localization at intercalated discs of cardiomyocytes and in peritubular myoid cells of testis.
AlphaT-catenin can functionally restore cell-cell adhesion in colon cancer cells lacking alpha-catenins, indicating involvement in specific muscle cell contacts. The encoded protein has an approximate size of 100 kDa and shares 57% amino acid identity with other alpha-catenins. In transfected cells, interaction with alpha-catenin was confirmed by coimmunoprecipitation. The 892_24D2S antibody against alphaT-catenin does not cross-react with alphaE-catenin or alphaN-catenin in western blot analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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