Thermo Fisher Scientific XPC Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt.
• Based on 100% sequence identity, this antibody is predicted to react with Dog, Orangutan, Monkey, Gorilla, and Chimpanzee.

Target Information

This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A–G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A.
XPC plays an important role in the early steps of global genome NER, particularly in damage recognition, open complex formation, and repair protein complex formation.
Mutations in this gene or other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight and early-onset carcinomas.
Alternatively spliced transcript variants have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.