Thermo Fisher Scientific CAS Recombinant Rabbit Monoclonal Antibody (JU34-33)
Thermo Fisher Scientific의 CAS Recombinant Rabbit Monoclonal Antibody (JU34-33)은 인간 CAS 단백질을 인식하는 고특이성 항체입니다. Western blot, IHC, ICC/IF, Flow Cytometry 등에 적합하며, 단백질 A로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JU34-33 |
| Immunogen | Recombinant protein within Human Cellular Apoptosis Susceptibility (aa 860–971) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848546 |
Product Specific Information
Positive Control: Mouse testis tissue, SiHa, SK-BR-3, PC-3M, LOVO, SH-SY5Y, human colon cancer tissue, LOVO.
Target Information
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- MA5-34638_CAS_P55060-1_Rabbit.svg
- MA5-34638_CAS_P55060-1_Rabbit_PDP.jpeg
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