Thermo Fisher Scientific CLDN3 Monoclonal Antibody (OTI1E7), TrueMAB
Human CLDN3 단백질을 인식하는 Mouse Monoclonal Antibody (OTI1E7). Western Blot과 IHC(Paraffin)에 적합. Lyophilized 형태로 제공되며, PBS buffer에 trehalose 포함. 연구용으로 다양한 암 조직의 Claudin 발현 연구에 활용 가능.
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Thermo Fisher Scientific CLDN3 Monoclonal Antibody (OTI1E7), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E7 |
| Immunogen | Full length human recombinant protein of human CLDN3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Claudin 1–8 proteins are transmembrane proteins associated with tight junctions, which act as molecular gaskets preventing leakage of ions and water between cells.
They are abundant in epithelial tissues and maintain cell polarity.
Differential expression of Claudin 3 has been observed in various malignancies including breast, ovarian, liver, urinary, prostate, lung, head and neck, and thyroid cancers.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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