Thermo Fisher Scientific Lactoferrin Monoclonal Antibody (5F12.1.2)

Applications

Western Blot (WB)

• Tested Dilution: 1:50

ELISA

• Tested Dilution: 1:50

Product Specifications

Product Specific Information

MA1-40262 detects Lactoferricin from bovine samples.
MA1-40262 has been successfully used in ELISA and Western blot applications.
The MA1-40262 immunogen is QWR region of Bovine Lactoferricin.

Target Information

Lactoferrin (LF) is an iron-binding glycoprotein composed of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each binding one ferric ion (Fe³⁺). It is found in milk, mucosal secretions, and neutrophil granules. LF plays key roles in:

• Iron homeostasis regulation
• Host defense against microbial infections
• Anti-inflammatory activity
• Cellular growth and differentiation
• Protection against cancer development and metastasis

Lactoferrin efficiently binds Fe³⁺ and exhibits bactericidal and proteolytic activities, cleaving arginine-rich microbial proteins. Three isoforms (LTF-α, LTF-β, LTF-γ) are known, and receptors are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and some bacteria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.