
Thermo Fisher Scientific Lactoferrin Monoclonal Antibody (5F12.1.2)
소 우유 유래 락토페리신(QWR 영역)을 인식하는 Mouse IgG1 단일클론 항체로, ELISA 및 Western blot에 사용 가능. 단백질 G 정제, PBS/BSA 버퍼에 0.1 mg/mL 농도로 제공되며 4°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:50
ELISA
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5F12.1.2 |
| Immunogen | QWR region of Bovine Lactoferricin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2139344 |
Product Specific Information
MA1-40262 detects Lactoferricin from bovine samples.
MA1-40262 has been successfully used in ELISA and Western blot applications.
The MA1-40262 immunogen is QWR region of Bovine Lactoferricin.
Target Information
Lactoferrin (LF) is an iron-binding glycoprotein composed of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each binding one ferric ion (Fe³⁺). It is found in milk, mucosal secretions, and neutrophil granules. LF plays key roles in:
- Iron homeostasis regulation
- Host defense against microbial infections
- Anti-inflammatory activity
- Cellular growth and differentiation
- Protection against cancer development and metastasis
Lactoferrin efficiently binds Fe³⁺ and exhibits bactericidal and proteolytic activities, cleaving arginine-rich microbial proteins. Three isoforms (LTF-α, LTF-β, LTF-γ) are known, and receptors are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and some bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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