Thermo Fisher Scientific DOCK5 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human DOCK5 protein. Validated for ICC/IF applications. Recombinant antigen-based immunogen ensures specificity. Supplied in liquid form with PBS and 40% glycerol. For research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human DOCK5. Recombinant protein control fragment (Product # RP-106733) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664784 |
Product Specific Information
Immunogen sequence:
VELSVLFCKFI QSIPDNQLVR QKLNCMTKIV ESTLFRQSEC REVLLPLLTD QLSGQLDDNS NKPDHEASSQ LL
- Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 92%
Target Information
Guanine nucleotide exchange factor (GEF) for Rho and Rac.
GEF proteins activate small GTPases by exchanging bound GDP for free GTP.
Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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