Thermo Fisher Scientific p38 MAPK beta Monoclonal Antibody (4H6H6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

4H6H6

Immunogen

Purified recombinant fragment of MAPK11 (aa251-363) expressed in E. Coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:p38 MAPK beta,uniProtId:Q15759-1,ncbiNodeId:9606,antigenRange:251-363,antigenLength:364,antigenImageFileName:MA5-15370_p38_MAPK_beta_Q15759-1_House_mouse.svg,antigenImageFileNamePDP:MA5-15370_p38_MAPK_beta_Q15759-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_11006226

Product Specific Information

MA5-15370 targets MAPK11 in indirect ELISA, WB applications and shows reactivity with Human samples.

The MA5-15370 immunogen is purified recombinant fragment of MAPK11 (aa251-363) expressed in E. Coli.

Target Information

MAPK11 (p38 beta) is a serine/threonine kinase which is involved in a variety of cellular processes, and is activated by proinflammatory cytokines and environmental stress. Mitogen-activated protein kinase 11. The protein encoded by p38 MAPK beta is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.