Thermo Fisher Scientific LGALS3 Monoclonal Antibody (UMAB189), UltraMAB
LGALS3 단백질을 인식하는 UMAB189 단클론 항체로 Western blot, IHC, ICC, ChIP 등 다양한 응용에 적합합니다. Human 시료 반응성이 있으며, Affinity chromatography로 정제된 Lyophilized 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:200 |
| ChIP assay (ChIP) | Assay-dependent |
| Peptide Array (Array) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB189 |
| Immunogen | Full length human recombinant protein of human LGALS3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Galactose-specific lectin that binds IgE. May mediate, with the α3β1 integrin, the stimulation by CSPG4 of endothelial cell migration.
Together with DMBT1, it is required for terminal differentiation of columnar epithelial cells during early embryogenesis.
In the nucleus, acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, monocyte/macrophage chemoattraction, opsonization of apoptotic neutrophils, and mast cell activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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