Thermo Fisher Scientific CLEC12A Monoclonal Antibody (4D5A8)
인간 CLEC12A(CD371) 인식하는 Mouse IgG2a 단일클론 항체로, WB, ICC/IF, Flow Cytometry, ELISA 등 다양한 응용에 적합. Protein G 정제, 1 mg/mL 농도, PBS + 0.05% sodium azide 저장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CLEC12A Monoclonal Antibody (4D5A8)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:500 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D5A8 |
| Immunogen | Purified recombinant fragment of human CLL1 (aa 65–265) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at −20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898413 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
CD371, also known as CLEC12A or Myeloid Inhibitory C-type Lectin-like receptor (MICL), is a highly glycosylated transmembrane receptor containing a cytoplasmic ITIM that associates with SHP1 and SHP2.
It is mainly expressed on granulocytes, monocytes, macrophages, and dendritic cells, including plasmacytoid dendritic cells.
Expression on NK cells remains controversial. Although its function is not fully understood, studies suggest a role in inflammation and LPS activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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