Thermo Fisher Scientific COPB2 Polyclonal Antibody
Thermo Fisher Scientific의 COPB2 Polyclonal Antibody는 인간 및 생쥐 시료에서 COPB2 단백질 검출에 적합합니다. Western blot, IHC, IP 등 다양한 응용에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 800 to 850 of human Coatomer Protein Complex, Subunit Beta 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, and Orangutan
Target Information
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, mediating biosynthetic protein transport from the ER via the Golgi to the trans-Golgi network.
It is required for budding from Golgi membranes and essential for retrograde Golgi-to-ER transport of dilysine-tagged proteins.
In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), small GTP-binding proteins.
The complex also influences Golgi structural integrity and the processing, activity, and endocytic recycling of LDL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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