Thermo Fisher Scientific COPB2 Polyclonal Antibody
Rabbit 폴리클로날 항체로 COPB2 단백질을 인식하며, WB, IHC, IP 등 다양한 응용에 사용 가능. 인간 단백질의 800–850번 잔기 영역을 면역원으로 제작. 비결합형 액상 형태로 제공되며, 4°C 보관 및 습빙 운송. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 800 to 850 of human Coatomer Protein Complex, Subunit Beta 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, and Orangutan.
Target Information
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, mediating biosynthetic protein transport from the ER through the Golgi to the trans-Golgi network. The coatomer complex is required for budding from Golgi membranes and is essential for retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, it can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), small GTP-binding proteins. The complex also influences Golgi structural integrity and the processing, activity, and endocytic recycling of LDL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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